Whole blood mitochondrial DNA copy number in depressed patients with and without a history of adverse childhood experiences: the role of blood cell composition
Our findings do not support an association between ACE or MDD and whole blood mtDNAcn. Considering blood cell composition may enhance the understanding of whole blood mtDNAcn findings in trauma‑ and MDD‑related research.
Authors
- Sonja Entringer (ORCID: https://orcid.org/0000-0002-9926-7076)
- Alexander Karabatsiakis (ORCID: https://orcid.org/0000-0002-5822-0108)
- D Martens
- Karin de Punder (ORCID: https://orcid.org/0000-0003-0510-9147)
- Christine C. Heim (ORCID: https://orcid.org/0000-0002-6580-6326)
- Linn K. Kuehl (ORCID: https://orcid.org/0000-0001-6871-6302)
- Christian Eric Deuter (ORCID: https://orcid.org/0000-0001-6880-5946)
- Bilbo Kipka
- Christian Otte
- Katja Wingenfeld
Institutions
- Pennsylvania State University (US)
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- University of California, Irvine (US)
- Centre for Mental Health (GB)
- Humboldt-Universität zu Berlin (DE)
- MSB Medical School Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Hasselt University (BE)
Publication Details
- Journal
- The World Journal of Biological Psychiatry
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1080/15622975.2025.2601134
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00