Identify GDPD3 as a key regulator of epithelial–mesenchymal transition and prostate adenocarcinoma progression via the LPA/LPAR1/AKT axis: transcriptomic and experimental study
This study underscores key molecular mechanisms underlying prostate cancer progression, with GDPD3 emerging as a potential therapeutic target.
Authors
- Xichun Zheng
- Chengwu He
- Xiangqiu Chen (ORCID: https://orcid.org/0000-0001-8432-5299)
- Tao Wu (ORCID: https://orcid.org/0000-0001-6704-4452)
- Tao He (ORCID: https://orcid.org/0009-0007-2593-7253)
- Qishan Long
- Qingyou Zheng
- Lin Hao
- Ziliang Ji
- Donglin Sun
- Qingchun Zhou
- Zhiqiang Wen
Institutions
- Sun Yat-sen University (CN)
- Jinan University (CN)
- Southern University of Science and Technology (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Second People's Hospital (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1637325
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00