Concurrent neurobrucellosis and central nervous system aspergillosis in an immunocompetent host: a case report

This case highlights the diagnostic challenges and rarity of coexisting neurobrucellosis and Aspergillus infection, a combination not previously reported in medical literature. Both conditions are uncommon in the central nervous system and typically affect immunocompromised patients, making diagnosis difficult due to nonspecific symptoms and broad differential diagnoses. The successful treatment of this unique case underscores the need for further research into managing such unusual co-infections.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-01-05
DOI
https://doi.org/10.1186/s13256-025-05766-2
Primary Topic
Brucella: diagnosis, epidemiology, treatment
Type
article
Field-Weighted Citation Impact
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article

Concurrent neurobrucellosis and central nervous system aspergillosis in an immunocompetent host: a case report

Anas Jouhar, Ola Emad Alasmar, Rawan Daboul, Inass Aitta et al.
Journal of Medical Case Reports
Brucella: diagnosis, epidemiology, treatment
article

Concurrent neurobrucellosis and central nervous system aspergillosis in an immunocompetent host: a case report

Anas Jouhar, Ola Emad Alasmar, Rawan Daboul, Inass Aitta, Judy Sharkatli
article en

Abstract

This case highlights the diagnostic challenges and rarity of coexisting neurobrucellosis and Aspergillus infection, a combination not previously reported in medical literature. Both conditions are uncommon in the central nervous system and typically affect immunocompromised patients, making diagnosis difficult due to nonspecific symptoms and broad differential diagnoses. The successful treatment of this unique case underscores the need for further research into managing such unusual co-infections.

Journal of Medical Case ReportsVol. 20(1)
Homs University (SY), Damascus Hospital (SY)
Good health and well-being
Openalex Percentile: Top 97%
Brucella: diagnosis, epidemiology, treatment
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