Dose-dependent effects of SGLT2 inhibitors on circadian blood pressure in hypertensive patients with diabetes: A systematic review and Bayesian network meta-analysis
SGLT2 inhibitors produced modest and consistent reductions in BP, with no evidence of dose-dependence or meaningful differences among agents. Safety events were not credibly increased. These findings support their use as adjunctive therapy in patients with diabetes and hypertension.
Authors
- Khatere Roozbehi (ORCID: https://orcid.org/0000-0002-4414-9216)
- Davood Semirani-Nezhad
- Anahita Hashempoor
- Arman Soltani Moghadam
- Keyvan Salehi
- Elham Ebrahimi
Institutions
- Ahvaz Jundishapur University of Medical Sciences (IR)
- University of Toledo Medical Center (US)
- University of Copenhagen (DK)
- Harvard University (US)
- University of South Florida (US)
- Gentofte Hospital (DK)
- Massachusetts General Hospital (US)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- International Journal of Cardiology Cardiovascular Risk and Prevention
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1016/j.ijcrp.2025.200569
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 30.73