Distinct fasting and postprandial bile acid responses following Roux-en-Y and one-anastomosis gastric bypass
RYGB and OAGB differentially modulate BA profiles over one year, with RYGB increasing secondary BAs and OAGB increasing taurine-conjugated primary BAs. These findings suggest distinct mechanisms contributing to their metabolic benefits.
Authors
- Jari E. Karppinen (ORCID: https://orcid.org/0000-0002-9886-9067)
- Anne Juuti (ORCID: https://orcid.org/0000-0002-9836-662X)
- Mikko Neuvonen (ORCID: https://orcid.org/0000-0002-7627-1638)
- Sini Heinonen
- Matti Jänis
- Per-Henrik Groop
- Kirsi H. Pietiläinen
- Tuure Saarinen
- Mikko Niemi
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Institute for Molecular Medicine Finland (FI)
- Folkhälsans Forskningscentrum (FI)
- Hospital District of Helsinki and Uusimaa (FI)
Publication Details
- Journal
- International Journal of Obesity
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1038/s41366-025-01999-9
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00