Primary Peritoneal Carcinomatosis: A Case Report

Primary peritoneal adenocarcinoma (PPC) is an uncommon malignancy that arises from the peritoneal lining and shares striking clinical, histopathological, and immunophenotypic similarities with epithelial ovarian carcinoma (EOC). Because both entities derive from Müllerian epithelium, distinguishing PPC from metastatic ovarian or gastrointestinal carcinoma poses a significant diagnostic challenge, particularly in the absence of detectable ovarian masses. Recognizing this rare entity is clinically relevant, as accurate classification influences prognosis, genetic counseling, and management strategies.

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Publication Details

Journal
Cureus
Published
2026-01-04
DOI
https://doi.org/10.7759/cureus.100774
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary Peritoneal Carcinomatosis: A Case Report

Anvitha Soundararajan, Barney Soskin, Rodrigo Furlan Silva Fabri
Cureus
Intraperitoneal and Appendiceal Malignancies
article

Primary Peritoneal Carcinomatosis: A Case Report

Anvitha Soundararajan, Barney Soskin, Rodrigo Furlan Silva Fabri
article en

Abstract

Primary peritoneal adenocarcinoma (PPC) is an uncommon malignancy that arises from the peritoneal lining and shares striking clinical, histopathological, and immunophenotypic similarities with epithelial ovarian carcinoma (EOC). Because both entities derive from Müllerian epithelium, distinguishing PPC from metastatic ovarian or gastrointestinal carcinoma poses a significant diagnostic challenge, particularly in the absence of detectable ovarian masses. Recognizing this rare entity is clinically relevant, as accurate classification influences prognosis, genetic counseling, and management strategies.

CureusVol. 18(1)
Texas Tech University (US), The University of Texas at El Paso (US)
Good health and well-being
Openalex Percentile: Top 97%
Intraperitoneal and Appendiceal Malignancies
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