Study on the correlation between plasma concentration of voriconazole and clinical efficacy and safety in elderly patients
Voriconazole plasma concentrations in elderly patients vary widely, and concentrations exceeding 4.5 μg/mL do not enhance efficacy but are associated with an increased risk of hepatotoxicity, warranting close monitoring in clinical practice.
Authors
- H Wang
- Wen Zhang (ORCID: https://orcid.org/0000-0001-9739-9799)
- Si Wang (ORCID: https://orcid.org/0000-0003-2431-0612)
- Huifang Xu
- Yujia Song
- Yueran Li
Institutions
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fphar.2025.1726902
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00