Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda

Combination of RAP and chemotherapy offers promising approach to control AAT in endemic areas and can support last mile acute sleeping sickness elimination efforts when combined with other available tsetse and AAT control methods. A singular infection with T. b. rhodesiense indicates that there is still a risk of acute sleeping sickness resurgence in south-eastern Uganda unless tsetse and trypanosomiasis control and surveillance efforts are maintained.

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Publication Details

Journal
BMC Veterinary Research
Published
2026-01-05
DOI
https://doi.org/10.1186/s12917-025-05244-3
Primary Topic
Trypanosoma species research and implications
Type
article
Field-Weighted Citation Impact
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article

Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda

Wilson Amanyire, Joseph Nkamwesiga, Albert Mugenyi, Dennis Muhanguzi et al.
BMC Veterinary Research
Trypanosoma species research and implications
article

Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda

Wilson Amanyire, Joseph Nkamwesiga, Albert Mugenyi, Dennis Muhanguzi, Karla Rascón-García, Auther Tamale Wasswa, Solomon Ainebyoona, Harriet Abizera, Mesearch Kakuru, Enock Matovu, Phillip Magambo Kimuda, Marvyn Kansiime, Patrick P’Odyek Abila
article en

Abstract

Combination of RAP and chemotherapy offers promising approach to control AAT in endemic areas and can support last mile acute sleeping sickness elimination efforts when combined with other available tsetse and AAT control methods. A singular infection with T. b. rhodesiense indicates that there is still a risk of acute sleeping sickness resurgence in south-eastern Uganda unless tsetse and trypanosomiasis control and surveillance efforts are maintained.

BMC Veterinary ResearchVol. 22(1)
Duke University (US), Ministry of Agriculture, Animal Industry and Fisheries (UG), Duke Institute for Health Innovation (US), National Agricultural Research Organisation (UG), International Livestock Research Institute (KE), Makerere University (UG), Freie Universität Berlin (DE)
Good health and well-being
Openalex Percentile: Top 97%
Trypanosoma species research and implications
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Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda — Wilson Amanyire, Joseph Nkamwesiga, et al. · BMC Veterinary Research (2026) | TGRS Research Map | TGRS