Identification of prognostic biomarkers and development of a prediction model for prostate cancer

We identified nine target genes and propose a three-gene prognostic model for outcome prediction in PCa. Our findings suggest that targeting PLXNA4 may offer new therapeutic opportunities for the treatment of PCa, including immunotherapy.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-05
DOI
https://doi.org/10.3389/fimmu.2025.1709264
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of prognostic biomarkers and development of a prediction model for prostate cancer

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Frontiers in Immunology
Ferroptosis and cancer prognosis
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Identification of prognostic biomarkers and development of a prediction model for prostate cancer

Jingyi Jia, Bowei Yin, Feilong Miao, RuXian Ye, Weiqing Ning, Linjin Li, Peter Wang, Xianghui Kong, Wu Chen, Qiuli Chen, Dake Chen
article en

Abstract

We identified nine target genes and propose a three-gene prognostic model for outcome prediction in PCa. Our findings suggest that targeting PLXNA4 may offer new therapeutic opportunities for the treatment of PCa, including immunotherapy.

Frontiers in ImmunologyVol. 16
Wenzhou Medical University (CN), Beijing Emergency Medical Center (CN), Wenzhou City People's Hospital (CN)
Openalex Percentile: Top 97%
Ferroptosis and cancer prognosis
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