Systemic inflammatory indices mediate the association between hyperuricemia and left ventricular hypertrophy: evidence from a single-center retrospective cross-sectional study
In HUA patients, SII and SIRI are positively correlated with LVH and partially mediate the relationship between urate and cardiac remodeling, emphasizing the role of systemic inflammation in hyperuricemia related cardiovascular diseases.
Authors
- Shuhui Hu (ORCID: https://orcid.org/0000-0003-1277-4364)
- Jingyuan Li (ORCID: https://orcid.org/0000-0002-1604-2227)
- Lei Chen
- Fengyao Sun
- Ying Chen
- Xiaoqing Zhang
- Ying Gong
- Ruting Li
- Yang Xu
- Xin Huang
- Fei Yan
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Health & Life (Taiwan) (TW)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fendo.2025.1742938
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China