In vitro antibiofilm activity of tyrosol against single and dual-species biofilms of Candida tropicalis and Streptococcus mutans

This study investigated the antimicrobial and antibiofilm properties of tyrosol against <i>C</i>. <i>tropicalis</i> and <i>S</i>. <i>mutans</i>, individually and in combination. The results showed that tyrosol inhibited growth and biofilm formation, particularly in dual-species biofilms. Although <i>S</i>. <i>mutans</i> had greater resistance, overall microbial viability was reduced. Despite some observed increase in AMP resistance, tyrosol was selectively cytotoxic, indicating its promise as a natural therapeutic agent pending further research.