Phytochemical Analysis and Hepatoprotective Activity of Amaranthus spinosus and Moringa oleifera

This study investigates the phytochemical composition and hepatoprotective potential of Amaranthus spinosus and Moringa oleifera. Extracts from both plants were subjected to comprehensive phytochemical screening to identify bioactive compounds. The hepatoprotective activity was evaluated using in vitro and in vivo models of liver injury. Phytochemical analysis revealed the presence of flavonoids, alkaloids, saponins, and phenolic compounds in both plant extracts. The extracts demonstrated significant antioxidant properties and exhibited protective effects against hepatotoxicity in experimental models. Treatment with the plant extracts resulted in reduced levels of liver enzymes, improved antioxidant status, and decreased histo pathological alterations in liver tissue. These findings suggest that Amaranthus spinosus and Moringa oleifera possess hepatoprotective properties, likely attributed to their rich phytochemical profiles. Further research is warranted to isolate and characterize the specific compounds responsible for these beneficial effects and to elucidate the underlying mechanisms of hepato-protection.

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Publication Details

Journal
International Journal of Novel Research and Development
Published
2025-12-01
DOI
https://doi.org/10.56975/ijnrd.v10i12.311376
Primary Topic
Moringa oleifera research and applications
Type
article
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article

Phytochemical Analysis and Hepatoprotective Activity of Amaranthus spinosus and Moringa oleifera

Kapil Soni, AMRITA KARIYARI
International Journal of Novel Research and Development
Moringa oleifera research and applications
article

Phytochemical Analysis and Hepatoprotective Activity of Amaranthus spinosus and Moringa oleifera

Kapil Soni, AMRITA KARIYARI
article en

Abstract

This study investigates the phytochemical composition and hepatoprotective potential of Amaranthus spinosus and Moringa oleifera. Extracts from both plants were subjected to comprehensive phytochemical screening to identify bioactive compounds. The hepatoprotective activity was evaluated using in vitro and in vivo models of liver injury. Phytochemical analysis revealed the presence of flavonoids, alkaloids, saponins, and phenolic compounds in both plant extracts. The extracts demonstrated significant antioxidant properties and exhibited protective effects against hepatotoxicity in experimental models. Treatment with the plant extracts resulted in reduced levels of liver enzymes, improved antioxidant status, and decreased histo pathological alterations in liver tissue. These findings suggest that Amaranthus spinosus and Moringa oleifera possess hepatoprotective properties, likely attributed to their rich phytochemical profiles. Further research is warranted to isolate and characterize the specific compounds responsible for these beneficial effects and to elucidate the underlying mechanisms of hepato-protection.

International Journal of Novel Research and DevelopmentVol. 10(12)
Barkatullah University (IN)
Openalex Percentile: Top 23%
Moringa oleifera research and applications
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