Clinical and molecular features of candidemia: a three-year retrospective study in Northern Guizhou, China

This study confirms that candidemia remains a serious threat with high mortality. The distinct risk factors and prognostic biomarkers between <i>C. albicans</i> and non-<i>C. albicans</i> species indicate the need for species-specific management. Although overall resistance remains low, emerging azole non-susceptibility in key species underscores the necessity for continuous susceptibility surveillance. MLST revealed a highly diverse and evolving <i>C. albicans</i> population, including novel genetic lineages. Integrating molecular epidemiology with clinical data is crucial for advancing global candidemia management.