Improved DCD Heart Transplant Function Through Ferroptosis Blockade in a Model of Experimental Normothermic Ex Vivo Perfusion
Normothermic EVHP combined with Lip-1 treatment can be a promising DCD heart preservation strategy, which can alleviate myocardial IRI, ameliorate endothelial dysfunction, and improve posttransplant cardiac function for DCD hearts via inhibiting myocardial ferroptosis.
Authors
- Peitao Zhou (ORCID: https://orcid.org/0000-0001-5094-3945)
- Zekai Huang (ORCID: https://orcid.org/0000-0002-4571-7086)
- Jianqiang Ji
- Zhong Zhang (ORCID: https://orcid.org/0000-0002-5605-4951)
- Jun Lu (ORCID: https://orcid.org/0000-0002-9878-9091)
- Liwei Xu (ORCID: https://orcid.org/0000-0002-6361-8479)
- Shaoyi Zheng
- Xiu Liu
- Xuan Pan
- Qinbao Peng
- Chuangjie Niu
Institutions
- Shantou University (CN)
- Nanfang Hospital (CN)
- Yue Bei People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Transplantation
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1097/tp.0000000000005606
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00