Can adaptive hyperactivation result in a positive score on the Mood Disorder Questionnaire? Evidence from a case-control study over a community survey
MDQ positivity identifies a heterogeneous population, including individuals with adaptive hyperactivation and preserved functioning. These findings highlight the need for more refined instruments capable of distinguishing adaptive from pathological hyperactivation and caution against over-pathologizing MDQ positivity in clinical and public health settings.
Authors
- Cesar Iván Avilés González (ORCID: https://orcid.org/0000-0002-1566-1974)
- Elisa Cantone (ORCID: https://orcid.org/0009-0001-5049-4614)
- M. Fornaro
- Federica Sancassiani (ORCID: https://orcid.org/0000-0002-7963-5281)
- Massimo Tusconi (ORCID: https://orcid.org/0000-0002-9155-4740)
- Elisa Pintus
- S. Dursun
- Antonio E. Nardi
- Mauro Giovanni Carta
- Michela Atzeni
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- University of Alberta (CA)
- University of Cagliari (IT)
- Università degli Studi di Enna Kore (IT)
- Popular University of Cesar (CO)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fpsyt.2025.1626277
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agenzia Italiana del Farmaco, Ministero della Salute