Divalent HIV-1 gp120 Immunogen Exhibits Selective Avidity for Broadly Neutralizing Antibody VRC01 Precursors
In light of these results, we are preparing for in vivo vaccination experiments to test the immune focusing properties of this immunogen, the results of which may suggest broad application of the selective avidity concept.
Authors
- Helmut Kae
- John M. Berestecky (ORCID: https://orcid.org/0009-0007-4917-991X)
- Ryan C. Bailey (ORCID: https://orcid.org/0000-0003-1021-4267)
- Albert To (ORCID: https://orcid.org/0000-0002-7118-9803)
- Axel T. Lehrer (ORCID: https://orcid.org/0000-0002-0518-203X)
- Brien K. Haun
- Ludwig I. Mayerlen (ORCID: https://orcid.org/0009-0002-4083-0802)
- Kalista Kahoekapu
- Gabriel Manninen
- Cecilia Shikuma
- Iain S. MacPherson
Institutions
- Leeward Community College (US)
- University of Hawaii System (US)
- Kapiolani Community College (US)
Publication Details
- Journal
- Vaccines
- Published
- 2026-01-03
- DOI
- https://doi.org/10.3390/vaccines14010058
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00