Interplay between oxidative stress and physical exercise in hospitalized older adults: a secondary analysis of an RCT using malondialdehyde as a biomarker
Structured exercise may mitigate the increase in oxidative stress in hospitalized older adults, particularly in women and those with diabetes. The magnitude of functional improvements could depend on baseline oxidative status, highlighting the need for personalized interventions. Future research should explore long-term effects, biomarkers, and tailored protocols to optimize outcomes in this population.
Authors
- Marco Riva (ORCID: https://orcid.org/0000-0003-1580-6966)
- Chenhui Chenhuichen (ORCID: https://orcid.org/0000-0001-9232-7497)
- Fabíola Zambom-Ferraresi (ORCID: https://orcid.org/0000-0001-7068-5269)
- Icíar Echeverría-Beistegui
- Patricia Álvarez-Rodríguez (ORCID: https://orcid.org/0009-0002-4529-7242)
- Maite Izco-Cubero
- Consuelo Borrás
- Nicolas Martínez-Velilla
- Pedro Azanon-Nogueira
- Fabricio Zambom-Ferraresi
Institutions
- Universidad Pública de Navarra (UPNA) (ES)
- Universidad Cardenal Herrera CEU (ES)
- Navarre Institute of Health Research (ES)
- Navarrabiomed (ES)
- Clinica Universidad de Navarra (ES)
- Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (ES)
- INCLIVA Health Research Institute (ES)
- Universidad de Navarra (ES)
Publication Details
- Journal
- Frontiers in Aging
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fragi.2025.1708162
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Generalitat Valenciana
- Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España
- Instituto de Salud Carlos III
- European Regional Development Fund