Eucommia ulmoides extract attenuates oxidative stress and promotes melanogenesis via Wnt/β-catenin signaling in B16 cells and mice

Our results demonstrate that EUE mitigates oxidative stress and promotes melanogenesis primarily by activating the Wnt/β-catenin-MITF signaling axis. These findings provide strong mechanistic evidence supporting EUE as a potential therapeutic strategy for oxidative stress-related hair graying.

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Publication Details

Journal
TURKISH JOURNAL OF BIOLOGY
Published
2025-12-29
DOI
https://doi.org/10.55730/1300-0152.2780
Primary Topic
Hair Growth and Disorders
Type
article
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article

Eucommia ulmoides extract attenuates oxidative stress and promotes melanogenesis via Wnt/β-catenin signaling in B16 cells and mice

Xiaobing Lv, Tiancheng JI, Yefan Gu, SHUYUE CHEN et al.
TURKISH JOURNAL OF BIOLOGY
Hair Growth and Disorders
article

Eucommia ulmoides extract attenuates oxidative stress and promotes melanogenesis via Wnt/β-catenin signaling in B16 cells and mice

Xiaobing Lv, Tiancheng JI, Yefan Gu, SHUYUE CHEN, XIAOJIN LIU, LEI CHANG, YAQIAN QIU
article en

Abstract

Our results demonstrate that EUE mitigates oxidative stress and promotes melanogenesis primarily by activating the Wnt/β-catenin-MITF signaling axis. These findings provide strong mechanistic evidence supporting EUE as a potential therapeutic strategy for oxidative stress-related hair graying.

TURKISH JOURNAL OF BIOLOGYVol. 49(7)
Anhui Normal University (CN)
Zero hunger
Openalex Percentile: Top 26%
Hair Growth and Disorders
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