Antibiotic susceptibility profile of bacterial isolates in paediatric cancer patients: a prospective cross-sectional study
BSIs constitute a significant complication in paediatric cancer patients in this Ghanaian centre. Meropenem and amikacin were highly effective against Gram-negative bacteria, whereas substantial resistance was observed to gentamicin and ceftriaxone. There is the need to revise the empiric fever protocol at the centre to consider amikacin instead of gentamicin, The emergence of MDR organisms underscores the need for robust antibiotic stewardship and infection control measures at the oncology clinic.
Authors
- Louis Gyekye Appiah (ORCID: https://orcid.org/0000-0002-5788-6768)
- Anita Nwachuku
- Lawrence Annison (ORCID: https://orcid.org/0000-0002-1485-8580)
- Henry Kwadwo Hackman (ORCID: https://orcid.org/0000-0003-1330-1622)
- Reuben Essel Arhin (ORCID: https://orcid.org/0000-0002-5726-4694)
- Ebenezer Krampah Aidoo
- Alice Constance Mensah
- Benjamin Ansah Agyei
- Ralph Bubune Gawugah
Institutions
- University of Cape Coast (GH)
- Accra Technical University (GH)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1186/s12887-025-06475-x
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00