Outcomes of pPCL Diagnosed Using the IMWG 2021 Consensus Definition: A Retrospective Multicenter Analysis
Our dataset represents one of the largest cohorts to date using the expanded definition of pPCL adopted by the IMWG in 2021 and stresses the importance of taking pPCL patients to transplant. Unfortunately, our study was not powered to determine the efficacy of individual induction and maintenance regimens, and many patients diagnosed with pPCL are ineligible for transplant based on end-organ damage at diagnosis or from disease that is refractory to induction therapy, underscoring the need for early diagnosis and treatment in hopes of preserving transplant eligibility.
Authors
- Christopher Sun Strouse (ORCID: https://orcid.org/0000-0003-4964-167X)
- Shebli Atrash (ORCID: https://orcid.org/0000-0003-4547-7534)
- Razan Mansour (ORCID: https://orcid.org/0000-0002-7719-9068)
- Ahmed Nausheen
- Akhil Jain (ORCID: https://orcid.org/0000-0001-7298-4246)
- Muhammad Umair Mushtaq
- Yara Shatnawi
- Barry Paul
- Al-Ola Abdallah
- Priyanka Venkatesh
Institutions
- Jordan University of Science and Technology (JO)
- University of Iowa Hospitals and Clinics (US)
- Yale Cancer Center (US)
- University of Alabama at Birmingham (US)
- Yale University (US)
- Levine Cancer Institute (US)
- University of Kansas Medical Center (US)
Publication Details
- Journal
- Cancers
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3390/cancers18010177
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00