Compartment-specific correlation of pathological α-synuclein in prodromal Parkinson's disease
The correlation of serum and stool α-synuclein suggests shared or linked pathology across these compartments, whereas the urinary compartment may be pathophysiologically distinct in prodromal Parkinson's Disease.
Authors
- Anja Ophey (ORCID: https://orcid.org/0000-0001-5858-7762)
- George K. Tofaris (ORCID: https://orcid.org/0000-0002-9252-5933)
- Michael Sommerauer (ORCID: https://orcid.org/0000-0001-5723-9766)
- Laura Müller
- Sinah Röttgen
- Michael T. Barbe
- Gereon R. Fink
- Gültekin Tamgüney
- Carolin Hungerland
- Shijun Yan
Institutions
- University of Cologne (DE)
- University of Oxford (GB)
- University Hospital Cologne (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Parkinsonism & Related Disorders
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1016/j.parkreldis.2026.108178
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- Else Kröner-Fresenius-Stiftung
- Universität zu Köln
- Medical Research Council