Comparative Analysis of Effectiveness of Dolutegravir-Based Regimen (TLD) vs. Efavirenz-Based Regimen (TLE) to Prevent Mother-to-Child Transmission of HIV

The TLD regimen was associated with a trend towards lower MTCT of HIV compared to the TLE regimen. Thus, continued use of dolutegravir-based therapy is recommended to support national and global goals of eliminating new HIV infections among exposed infants.

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Publication Details

Journal
Cureus
Published
2026-01-05
DOI
https://doi.org/10.7759/cureus.100824
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative Analysis of Effectiveness of Dolutegravir-Based Regimen (TLD) vs. Efavirenz-Based Regimen (TLE) to Prevent Mother-to-Child Transmission of HIV

Aruna Verma, Monika Kashyap, Deepti Pathak, Mitali Gupta et al.
Cureus
HIV/AIDS drug development and treatment
article

Comparative Analysis of Effectiveness of Dolutegravir-Based Regimen (TLD) vs. Efavirenz-Based Regimen (TLE) to Prevent Mother-to-Child Transmission of HIV

Aruna Verma, Monika Kashyap, Deepti Pathak, Mitali Gupta, Sandhya Gautam
article en

Abstract

The TLD regimen was associated with a trend towards lower MTCT of HIV compared to the TLE regimen. Thus, continued use of dolutegravir-based therapy is recommended to support national and global goals of eliminating new HIV infections among exposed infants.

CureusVol. 18(1)
Lala Lajpat Rai Memorial Medical College (IN), Bir Hospital (NP)
Good health and well-being
Openalex Percentile: Top 98%
HIV/AIDS drug development and treatment
DOIOpen Access PDFOpenAlex
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