Transcriptomics driven identification of hub gene miRNA interactions for biomarker and therapeutic target discovery in gynecological cancers

The identified miRNAs exhibit strong regulatory interactions with these hub genes, while serine/threonine protein kinases emerged as the most significantly associated group. Together, these findings highlight promising biomarker candidates and potential therapeutic targets for gynecological cancers.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-05
DOI
https://doi.org/10.3389/fonc.2025.1719597
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomics driven identification of hub gene miRNA interactions for biomarker and therapeutic target discovery in gynecological cancers

Mei Cao, WangBo Liu, Hanling Huang, Yuanjun Zhu et al.
Frontiers in Oncology
MicroRNA in disease regulation
article

Transcriptomics driven identification of hub gene miRNA interactions for biomarker and therapeutic target discovery in gynecological cancers

Mei Cao, WangBo Liu, Hanling Huang, Yuanjun Zhu, Ke Huang, Lingling Shi, Sisi Chen
article en

Abstract

The identified miRNAs exhibit strong regulatory interactions with these hub genes, while serine/threonine protein kinases emerged as the most significantly associated group. Together, these findings highlight promising biomarker candidates and potential therapeutic targets for gynecological cancers.

Frontiers in OncologyVol. 15
Hubei University of Medicine (CN), Taihe Hospital (CN)
Good health and well-being
Openalex Percentile: Top 97%
MicroRNA in disease regulation
DOIOpen Access PDFOpenAlex
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Transcriptomics driven identification of hub gene miRNA interactions for biomarker and therapeutic target discovery in gynecological cancers — Mei Cao, WangBo Liu, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS