Recombinant Human Soluble Thrombomodulin and In-Hospital Mortality in Acute Pancreatitis With Disseminated Intravascular Coagulation: A Japanese Nationwide Study

Administration of rTM in patients with AP complicated by DIC was associated with lower in-hospital mortality.

Authors

Atsuto Kayashima (ORCID: https://orcid.org/0000-0002-3981-2984)
Yuya Kimura (ORCID: https://orcid.org/0000-0003-1649-0596)
Tsubasa Sato
T. Kanai
Yusuke Sasabuchi (ORCID: https://orcid.org/0000-0001-7828-0549)
F. Bazerbachi
Hiroki Matsui (ORCID: https://orcid.org/0000-0003-3243-333X)
Kiyohide Fushimi (ORCID: https://orcid.org/0000-0002-1894-0290)
Masayasu Horibe
Hideo Yasunaga
Haruka Okada
Eisuke Iwasaki

Institutions

University of Minnesota (US)
Keio University (JP)
St. Cloud Hospital (US)
Tokyo Medical Center (JP)
University of Tokyo Health Sciences (JP)
National Hospital Organization (JP)
The University of Tokyo (JP)

Publication Details

Journal: Critical Care Medicine
Published: 2026-01-02
DOI: https://doi.org/10.1097/ccm.0000000000007009
Primary Topic: Pancreatitis Pathology and Treatment
Type: article
Field-Weighted Citation Impact: 0.00

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article

Recombinant Human Soluble Thrombomodulin and In-Hospital Mortality in Acute Pancreatitis With Disseminated Intravascular Coagulation: A Japanese Nationwide Study

Atsuto Kayashima, Yuya Kimura, Tsubasa Sato, T. Kanai et al.

Jan 2, 2026

Critical Care Medicine

Pancreatitis Pathology and Treatment

article

Recombinant Human Soluble Thrombomodulin and In-Hospital Mortality in Acute Pancreatitis With Disseminated Intravascular Coagulation: A Japanese Nationwide Study

Atsuto Kayashima, Yuya Kimura, Tsubasa Sato, T. Kanai, Yusuke Sasabuchi, F. Bazerbachi, Hiroki Matsui, Kiyohide Fushimi, Masayasu Horibe, Hideo Yasunaga, Haruka Okada, Eisuke Iwasaki

January 2, 2026article en

Abstract

Administration of rTM in patients with AP complicated by DIC was associated with lower in-hospital mortality.

Critical Care MedicineVol. 54(3)

University of Minnesota (US), Keio University (JP), St. Cloud Hospital (US), Tokyo Medical Center (JP), University of Tokyo Health Sciences (JP), National Hospital Organization (JP), The University of Tokyo (JP)

Good health and well-being

Openalex Percentile: Top 97%

Pancreatitis Pathology and Treatment

DOI Source OpenAlex

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Recombinant Human Soluble Thrombomodulin and In-Hospital Mortality in Acute Pancreatitis With Disseminated Intravascular Coagulation: A Japanese Nationwide Study — Atsuto Kayashima, Yuya Kimura, et al. · Critical Care Medicine (2026) | TGRS Research Map | TGRS