Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, <scp>EpiCARE</scp>
This position paper, developed by the European Reference Network for Rare and Complex Epilepsies (EpiCARE) in collaboration with its Patient Advocacy Group, defines six areas of research priorities in epilepsy. Each section describes key challenges, current knowledge, and areas for improvement. They focus on preventing epilepsy, developing targeted therapies, improving surgery and clinical trials, using artificial intelligence to support diagnosis, and addressing comorbidities such as cognition, sleep, and overall health. Each provides a roadmap for clinicians and researchers to guide their research projects within their areas of expertise. Collectively, these priorities converge on actions for improving diagnosis, treatment, and patient outcomes through European collaboration and sustainable research efforts.
Authors
- Floor E. Jansen (ORCID: https://orcid.org/0000-0003-0745-5668)
- Rima Nabbout (ORCID: https://orcid.org/0000-0001-5877-4074)
- Isabella Brambilla (ORCID: https://orcid.org/0000-0002-9860-8246)
- Andreas Brunklaus (ORCID: https://orcid.org/0000-0002-7728-6903)
- Amy McTague (ORCID: https://orcid.org/0000-0002-0334-2909)
- Alexis A. Arzimanoglou (ORCID: https://orcid.org/0000-0002-7233-2771)
- C. E. Helmstaedter
- R. Surges
- L. Lagae
- Sophie Adler (ORCID: https://orcid.org/0000-0002-3978-7424)
- Rikke S. Møller (ORCID: https://orcid.org/0000-0002-9664-1448)
- Eugen Trinka (ORCID: https://orcid.org/0000-0002-5950-2692)
- Valentina De Giorgis (ORCID: https://orcid.org/0000-0001-9265-7381)
- Sébile Tchaicha
- Masa Malenica
- Katarzyna Kotulska (ORCID: https://orcid.org/0000-0002-6848-4916)
- Kees Braun
- Stéphane Auvin
- Ingmar Blümcke
- Małgorzata Kosla
- Sándor Beniczky
- Nicola Specchio
- Guido Rubboli
- Gaetan Lesca
- J. Helen Cross
- Philippe Ryvlin
- Sandra Silva Arrieta
- Emilio Perucca
Institutions
- University of Copenhagen (DK)
- Hôpital Necker-Enfants Malades (FR)
- Advocates for Youth (US)
- Hospital Sant Joan de Déu Barcelona (ES)
- Inserm (FR)
- The University of Melbourne (AU)
- University of Southern Denmark (DK)
- Institut Universitaire de France (FR)
- Université Paris Cité (FR)
- University of Pavia (IT)
- Paracelsus Medical University (AT)
- University Hospital Bonn (DE)
- Great Ormond Street Hospital (GB)
- Royal Hospital for Children (GB)
- Austin Hospital (AU)
- Centre Hospitalier Universitaire Vaudois (CH)
- Aarhus University Hospital (DK)
- Foundation Center (US)
- University Medical Center Utrecht (NL)
- Epilepsy Research UK (GB)
- Universitätsklinikum Erlangen (DE)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Urology Foundation (GB)
- Christian Doppler Klinik (AT)
- Children's Memorial Health Institute (PL)
- Bambino Gesù Children's Hospital (IT)
- Sisters of Charity Hospital (HR)
- Hôpital Robert-Debré (FR)
- ERN GUARD-Heart (NL)
- Epilepsy Action (GB)
- Centre For Irish and European Security (IE)
- Electronic Product Services (Czechia) (CZ)
- Epilepsy Foundation (AU)
- Patient Advocate Foundation (US)
- Karl Landsteiner Society (AT)
- Institut des Maladies Génétiques Imagine (FR)
- NeuroDiderot (FR)
- Institut de Recerca Sant Joan de Déu
- University College London (GB)
- Monash University (AU)
- KU Leuven (BE)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1002/epi4.70210
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission