A gene signature associated with alpha-linolenic acid metabolism predicts clinical prognosis in hepatocellular carcinoma
This study provides a comprehensive analysis of ALA metabolism-associated genes in HCC and proposes a novel risk-based prognostic framework. The developed model demonstrates strong predictive performance for patient survival outcomes, representing the first such approach with robust validation in forecasting prognosis in HCC.
Authors
- Qingmiao Shi
- Zeyu Wu
- Xinjun Hu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1186/s40001-025-03762-2
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00