A gene signature associated with alpha-linolenic acid metabolism predicts clinical prognosis in hepatocellular carcinoma

This study provides a comprehensive analysis of ALA metabolism-associated genes in HCC and proposes a novel risk-based prognostic framework. The developed model demonstrates strong predictive performance for patient survival outcomes, representing the first such approach with robust validation in forecasting prognosis in HCC.

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Publication Details

Journal
European journal of medical research
Published
2026-01-05
DOI
https://doi.org/10.1186/s40001-025-03762-2
Primary Topic
Fatty Acid Research and Health
Type
article
Field-Weighted Citation Impact
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article

A gene signature associated with alpha-linolenic acid metabolism predicts clinical prognosis in hepatocellular carcinoma

Qingmiao Shi, Zeyu Wu, Xinjun Hu
European journal of medical research
Fatty Acid Research and Health
article

A gene signature associated with alpha-linolenic acid metabolism predicts clinical prognosis in hepatocellular carcinoma

Qingmiao Shi, Zeyu Wu, Xinjun Hu
article en

Abstract

This study provides a comprehensive analysis of ALA metabolism-associated genes in HCC and proposes a novel risk-based prognostic framework. The developed model demonstrates strong predictive performance for patient survival outcomes, representing the first such approach with robust validation in forecasting prognosis in HCC.

European journal of medical researchVol. 31(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), National Cancer Center (US), First Affiliated Hospital of Henan University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 97%
Fatty Acid Research and Health
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