Cell senescence-related pathogenic genes in sleep disorders: a multi-omics Mendelian randomization study
Our multi-omics MR analysis has identified BLK, CTSB, TP53INP1, DNMT3A, ITPR1, and SLC16A7 as pivotal factors in the pathogenesis of sleep disorders. These findings provide a foundation for innovative early interventions and therapeutic strategies for sleep disorders.
Authors
- Li Tang (ORCID: https://orcid.org/0000-0001-5929-6975)
- Jinying Li (ORCID: https://orcid.org/0000-0003-1362-1757)
- Suchun Ding
- Xingbo Zhang
- Wanwei Jiang
Institutions
- Dalian Medical University (CN)
- Yuhuangding Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Affiliated Zhongshan Hospital of Dalian University (CN)
Publication Details
- Journal
- European Archives of Psychiatry and Clinical Neuroscience
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1007/s00406-025-02170-1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00