Retained Amniochorionic Tissue Managed with Office Hysteroscopy Using a 16 Fr Bipolar Mini-Resectoscope Under Nitrous Oxide Analgesia: A Case Report of “Positive Hysteroscopy”

Background: Retained products of conception (RPOC) after term delivery are uncommon but may lead to persistent abnormal uterine bleeding and other complications. Hysteroscopic removal is considered the optimal management strategy, and technological advances have increasingly enabled operative procedures to be performed safely in an office setting. Clinical case: We report the case of a 43-year-old woman who presented with intermittent spotting four months after spontaneous vaginal delivery. Transvaginal ultrasound revealed a small, avascular hyperechoic intrauterine lesion consistent with retained amniochorionic tissue. She underwent office hysteroscopic removal using a 16 Fr bipolar mini-resectoscope under nitrous oxide (N2O) buccal–nasal analgesia. The procedure was performed using a vaginoscopic, no-touch approach without speculum, tenaculum, or cervical dilation. Complete resection was achieved in a seven-minute procedure, with a postoperative pain score of 2/10 on the VAS and no complications. At 30-day follow-up, the patient was asymptomatic, and an ultrasound confirmed complete resolution. Conclusion: This case demonstrates that retained amniochorionic tissue can be safely and effectively treated in a fully ambulatory setting using mini-resectoscopic technology and N2O analgesia. The combination of minimally invasive instruments, patient-centered procedural strategies, and well-tolerated analgesia supports the growing role of office operative hysteroscopy for selected complex intrauterine conditions.

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Publication Details

Journal
Reproductive Medicine
Published
2026-01-05
DOI
https://doi.org/10.3390/reprodmed7010003
Primary Topic
Gynecological conditions and treatments
Type
article
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article

Retained Amniochorionic Tissue Managed with Office Hysteroscopy Using a 16 Fr Bipolar Mini-Resectoscope Under Nitrous Oxide Analgesia: A Case Report of “Positive Hysteroscopy”

Alessandro Libretti, Bianca Masturzo, Giovanni Lipari, Alessandro Messina et al.
Reproductive Medicine
Gynecological conditions and treatments
article

Retained Amniochorionic Tissue Managed with Office Hysteroscopy Using a 16 Fr Bipolar Mini-Resectoscope Under Nitrous Oxide Analgesia: A Case Report of “Positive Hysteroscopy”

Alessandro Libretti, Bianca Masturzo, Giovanni Lipari, Alessandro Messina, Tiziana Bruno, Paolo Alessi, Sofia Vegro, Daniele De Ruvo, Daniela Caronia, Livio Leo
article en

Abstract

Background: Retained products of conception (RPOC) after term delivery are uncommon but may lead to persistent abnormal uterine bleeding and other complications. Hysteroscopic removal is considered the optimal management strategy, and technological advances have increasingly enabled operative procedures to be performed safely in an office setting. Clinical case: We report the case of a 43-year-old woman who presented with intermittent spotting four months after spontaneous vaginal delivery. Transvaginal ultrasound revealed a small, avascular hyperechoic intrauterine lesion consistent with retained amniochorionic tissue. She underwent office hysteroscopic removal using a 16 Fr bipolar mini-resectoscope under nitrous oxide (N2O) buccal–nasal analgesia. The procedure was performed using a vaginoscopic, no-touch approach without speculum, tenaculum, or cervical dilation. Complete resection was achieved in a seven-minute procedure, with a postoperative pain score of 2/10 on the VAS and no complications. At 30-day follow-up, the patient was asymptomatic, and an ultrasound confirmed complete resolution. Conclusion: This case demonstrates that retained amniochorionic tissue can be safely and effectively treated in a fully ambulatory setting using mini-resectoscopic technology and N2O analgesia. The combination of minimally invasive instruments, patient-centered procedural strategies, and well-tolerated analgesia supports the growing role of office operative hysteroscopy for selected complex intrauterine conditions.

Reproductive MedicineVol. 7(1)
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT), Ospedale degli Infermi (IT), Affidea (CH), Azienda Ospedaliero Universitaria Maggiore della Carita (IT), Azienda USL della Valle d’Aosta (IT), University of Aosta Valley (IT), Azienda Ospedaliera Ospedale Maggiore (IT), Ospedale degli Infermi (IT)
Gender equality
Openalex Percentile: Top 98%
Gynecological conditions and treatments
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