Efficacy of Low-Dose Tolvaptan for Treatment of Profound Hyponatremia in Syndrome of Inappropriate Antidiuresis (SIAD): The EFFLUX-FLUID TRIAL
Low-dose tolvaptan effectively and rapidly increases [Na<sup>+</sup>] in SIAD patients with predictors of fluid restriction failure, with acceptable safety under close monitoring.
Authors
- Pattharawin Pattharanitima (ORCID: https://orcid.org/0000-0002-6010-0033)
- Pajaree Krisanapan
- Pichaya Tantiyavarong (ORCID: https://orcid.org/0000-0003-0793-794X)
- Sutatip Chinpraditsuk
- Narongchai Jaiyen
Institutions
- Thammasat University (TH)
- Thammasat University Hospital (TH)
- Phramongkutklao Hospital (TH)
- Udon Thani Hospital (TH)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1016/j.xkme.2025.101239
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00