Efficacy of dual-target iTBS on gait function and brain activation in stroke patients: a randomized, single-blinded, sham-controlled study
Simultaneous iTBS targeting the affected lower limb motor cortex and the contralateral cerebellar motor region is more effective than single-target stimulation in enhancing lower limb motor function and balance in stroke patients. This enhanced efficacy may arise from the activation of cortical-cerebellar circuits, which improves brain network efficiency and results in better gait outcomes.
Authors
- Sijie Sun (ORCID: https://orcid.org/0000-0002-4786-6819)
- Y Chen
- Luoyi Deng
- Shuang Wu
- Jing Zhang
- Xiaofeng Zhang
- Xianbin Wang
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fneur.2025.1678850
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China