Efficacy of dual-target iTBS on gait function and brain activation in stroke patients: a randomized, single-blinded, sham-controlled study

Simultaneous iTBS targeting the affected lower limb motor cortex and the contralateral cerebellar motor region is more effective than single-target stimulation in enhancing lower limb motor function and balance in stroke patients. This enhanced efficacy may arise from the activation of cortical-cerebellar circuits, which improves brain network efficiency and results in better gait outcomes.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-05
DOI
https://doi.org/10.3389/fneur.2025.1678850
Primary Topic
Transcranial Magnetic Stimulation Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy of dual-target iTBS on gait function and brain activation in stroke patients: a randomized, single-blinded, sham-controlled study

Sijie Sun, Y Chen, Luoyi Deng, Shuang Wu et al.
Frontiers in Neurology
Transcranial Magnetic Stimulation Studies
article

Efficacy of dual-target iTBS on gait function and brain activation in stroke patients: a randomized, single-blinded, sham-controlled study

Sijie Sun, Y Chen, Luoyi Deng, Shuang Wu, Jing Zhang, Xiaofeng Zhang, Xianbin Wang
article en

Abstract

Simultaneous iTBS targeting the affected lower limb motor cortex and the contralateral cerebellar motor region is more effective than single-target stimulation in enhancing lower limb motor function and balance in stroke patients. This enhanced efficacy may arise from the activation of cortical-cerebellar circuits, which improves brain network efficiency and results in better gait outcomes.

Frontiers in NeurologyVol. 16
Guiyang Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 97%
Transcranial Magnetic Stimulation Studies
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