Diagnostic Significance of Phase-Resolved Functional Lung Low-field Magnetic Resonance Imaging in Comparison to Photon-Counting CT and Pulmonary Function Tests in Connective Tissue Disease-associated Interstitial Lung Diseases

The feasibility of PREFUL using low-field MRI was demonstrated in patients with CTD-ILD. Several correlations between PREFUL and PFT parameters were found, indicating that MRI can quantify lung function impairment. Nevertheless, CT remains the gold standard for CTD-ILD assessment and further research in PREFUL is needed.

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Publication Details

Journal
Journal of Thoracic Imaging
Published
2026-01-05
DOI
https://doi.org/10.1097/rti.0000000000000872
Primary Topic
Atomic and Subatomic Physics Research
Type
article
Field-Weighted Citation Impact
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article

Diagnostic Significance of Phase-Resolved Functional Lung Low-field Magnetic Resonance Imaging in Comparison to Photon-Counting CT and Pulmonary Function Tests in Connective Tissue Disease-associated Interstitial Lung Diseases

Christoph Moenninghoff, Lynn Johann Frohwein, Andreas Voskrebenzev, Iram Shahzadi et al.
Journal of Thoracic Imaging
Atomic and Subatomic Physics Research
article

Diagnostic Significance of Phase-Resolved Functional Lung Low-field Magnetic Resonance Imaging in Comparison to Photon-Counting CT and Pulmonary Function Tests in Connective Tissue Disease-associated Interstitial Lung Diseases

Christoph Moenninghoff, Lynn Johann Frohwein, Andreas Voskrebenzev, Iram Shahzadi, Assmann Gunter, Robert Grimm, Julius Henning Niehoff, Michael Schmidt, Jens Vogel-Claussen, Saher Saeed, Jan Borggrefe, Ramona Muecke
article en

Abstract

The feasibility of PREFUL using low-field MRI was demonstrated in patients with CTD-ILD. Several correlations between PREFUL and PFT parameters were found, indicating that MRI can quantify lung function impairment. Nevertheless, CT remains the gold standard for CTD-ILD assessment and further research in PREFUL is needed.

Journal of Thoracic Imaging
Siemens (Germany) (DE), Medizinische Hochschule Hannover (DE), German Center for Lung Research (DE), Siemens Healthcare (United States) (US), Siemens Healthineers (Germany) (DE), Johannes Wesling Klinikum Minden (DE)
Openalex Percentile: Top 95%
Atomic and Subatomic Physics Research
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