Prevalence and genotype distribution of human papillomavirus infection among women in Chengdu, China between 2020 and 2024

The high and increasing HPV prevalence in Chengdu, along with its bimodal age distribution, seasonal variation, and frequent HR-LR co-infections-highlights the need for targeted interventions. HPV genotyping is recommended for patients with genital warts, particularly prior to procedures such as excision, to identify high-risk co-infections. A dual strategy of "vaccination and standardized screening" should be reinforced, including promoting the 9-valent vaccine (covering HPV-16/52/58) among young women and enhanced systematic screening for middle-aged and older women to control the second infection peak.