Comparison of Optimal and Excess Fresh Gas Flow for Pre-intubation Oxygenation: A Randomized, Participant-Blind, Non-inferiority Study

Pre-intubation oxygenation using the optimal FGF is non-inferior to excess FGF, and is as adequate as using excess FGF to achieve FeO<sub>2</sub> levels exceeding 85% during machine-delivered PS-based ventilation. However, it was noted that three minutes was insufficient to achieve the target FeO<sub>2</sub> 90% using a closed circuit system and concurrent volatile agents.

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Publication Details

Journal
Cureus
Published
2026-01-05
DOI
https://doi.org/10.7759/cureus.100807
Primary Topic
Airway Management and Intubation Techniques
Type
article
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0.00
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article

Comparison of Optimal and Excess Fresh Gas Flow for Pre-intubation Oxygenation: A Randomized, Participant-Blind, Non-inferiority Study

Subrata K Singha, Girish C Pathak, Habib Md R Karim, Chinmaya K Panda et al.
Cureus
Airway Management and Intubation Techniques
article

Comparison of Optimal and Excess Fresh Gas Flow for Pre-intubation Oxygenation: A Randomized, Participant-Blind, Non-inferiority Study

Subrata K Singha, Girish C Pathak, Habib Md R Karim, Chinmaya K Panda, Jitendra V Kalbande
article en

Abstract

Pre-intubation oxygenation using the optimal FGF is non-inferior to excess FGF, and is as adequate as using excess FGF to achieve FeO<sub>2</sub> levels exceeding 85% during machine-delivered PS-based ventilation. However, it was noted that three minutes was insufficient to achieve the target FeO<sub>2</sub> 90% using a closed circuit system and concurrent volatile agents.

CureusVol. 18(1)
All India Institute of Medical Sciences Raipur (IN), Gauhati Medical College and Hospital (IN), Government Medical College (IN), Nagpur Institute of Technology (IN), Central India Institute of Medical Sciences (IN), All India Institute of Medical Sciences, Nagpur (IN)
Clean water and sanitation
Openalex Percentile: Top 95%
Airway Management and Intubation Techniques
DOIOpen Access PDFOpenAlex
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Comparison of Optimal and Excess Fresh Gas Flow for Pre-intubation Oxygenation: A Randomized, Participant-Blind, Non-inferiority Study — Subrata K Singha, Girish C Pathak, et al. · Cureus (2026) | TGRS Research Map | TGRS