Changing in blood cells for infection detection: “Monocyte distribution width” acts as a key determinant in differentiating localized and blood stream infections
In ED patients with suspected infection, MDW is a highly effective biomarker for the early detetion of BSI, demonstrating significantly higher diagnostic accuracy than PCT and CRP in this study. Its ability to help stratify patients with localized versus systemic infection and to predict mortality makes it a valuable tool for early risk assessment and clinical decision-making.
Authors
- Raffaella Pavani (ORCID: https://orcid.org/0000-0001-5970-588X)
- Giulio Camarlinghi (ORCID: https://orcid.org/0000-0002-5798-9206)
- Maurizio Zanobetti (ORCID: https://orcid.org/0000-0003-0798-1393)
- Eva Maria Parisio (ORCID: https://orcid.org/0000-0002-2883-669X)
- Maria Lorubbio (ORCID: https://orcid.org/0000-0003-2786-0994)
- Danilo Tacconi
- Claudia Artini
- Novi Tommaso
- Agostino Ognibene
- Sara Montemerani
Institutions
- Ospedale San Donato (IT)
- Azienda Usl Toscana Centro (IT)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1016/j.cca.2026.120819
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00