Development and validation of a clinical model for predicting 90-day outcomes after endovascular therapy with adjunctive tirofiban in acute ischemic stroke

We developed and validated a pragmatic prediction model incorporating readily available clinical and procedural variables to estimate the risk of 90-day poor outcome in AIS-LVO patients treated with EVT and tirofiban. This tool may assist clinicians in individualized outcome prediction and inform adjunctive antithrombotic strategies in neurovascular care.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-05
DOI
https://doi.org/10.3389/fneur.2025.1729880
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
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article

Development and validation of a clinical model for predicting 90-day outcomes after endovascular therapy with adjunctive tirofiban in acute ischemic stroke

Tianhao Zhang, Hanye Yuan, Zheng Sun, D. Liu et al.
Frontiers in Neurology
Acute Ischemic Stroke Management
article

Development and validation of a clinical model for predicting 90-day outcomes after endovascular therapy with adjunctive tirofiban in acute ischemic stroke

Tianhao Zhang, Hanye Yuan, Zheng Sun, D. Liu, Minghui Du, Zhigang Liang, Hongchun Wei, Zhuqing Luan
article en

Abstract

We developed and validated a pragmatic prediction model incorporating readily available clinical and procedural variables to estimate the risk of 90-day poor outcome in AIS-LVO patients treated with EVT and tirofiban. This tool may assist clinicians in individualized outcome prediction and inform adjunctive antithrombotic strategies in neurovascular care.

Frontiers in NeurologyVol. 16
Qingdao University (CN), Binzhou Medical University (CN), Shandong University of Aeronautics (CN), Yuhuangding Hospital (CN), Affiliated Hospital of Qingdao University (CN), National Clinical Research (US)
Good health and well-being
Openalex Percentile: Top 98%
Acute Ischemic Stroke Management
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