Integrative multi-omics analysis reveals gut microbiota-derived metabolites and immune regulatory pathways in osteoarthritis pathogenesis
These findings provide new insights into the gut-joint axis, suggesting that targeting microbial metabolites and immune regulatory pathways may offer potential therapeutic strategies for OA and pave the way for future in vitro and in vivo investigations.
Authors
- M. Zhang (ORCID: https://orcid.org/0009-0003-3694-2040)
- Luodan Wang
- Hongwei Liu
- Weijiang Wang
Institutions
- Shanxi Medical University (CN)
- Second People 's Hospital of Jinzhong (CN)
- Taizhou Municipal Hospital (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1186/s13018-025-06604-3
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 46.80