Polydopamine-encapsulated modified Pulsatilla decoction: a strategy to enhance ulcerative colitis therapy
This study indicates that PDA@MPD prolongs colonic retention and is associated with modest improvements in DSS-induced colonic damage and inflammation in mice. These findings may offer a proof-of-concept for exploring polydopamine-based delivery systems in TCM formulations.
Authors
- Yijun Zhu (ORCID: https://orcid.org/0000-0003-2496-5395)
- Daoben Hua (ORCID: https://orcid.org/0000-0003-1813-6988)
- Ying-Jian Chen
- Tingting Wu (ORCID: https://orcid.org/0000-0002-6229-7319)
- Cheng-Qi LI
- Chang Liu
- Hong-Wen Sun
- Jing-Jing Wu
- Hui-Ping Zhu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Soochow University (CN)
- Suzhou Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2026-01-04
- DOI
- https://doi.org/10.1186/s13020-025-01280-1
- Primary Topic
- Polymer Surface Interaction Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Nanjing University of Chinese Medicine
- Nanjing University