Rewriting Diabetes Therapy: How Incretin Modulation is Transforming Cardiovascular and Renal Outcomes

Incretin-based therapy has shifted care from glucose-centric targets to cardiorenal risk reduction. GLP-1RA are guideline-endorsed for patients with T2DM and high CV/renal risk irrespective of HbA1c; dual agonists and oral small-molecule agents may broaden indications pending definitive outcome evidence.

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Publication Details

Journal
Diabetes Therapy
Published
2026-01-05
DOI
https://doi.org/10.1007/s13300-025-01829-1
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Rewriting Diabetes Therapy: How Incretin Modulation is Transforming Cardiovascular and Renal Outcomes

Luís Corral-Gudino, Miriam Gabella-Martín, Álvaro Rodrigo-Alaíz, José Pablo Miramontes-González et al.
Diabetes Therapy
Diabetes Treatment and Management
article

Rewriting Diabetes Therapy: How Incretin Modulation is Transforming Cardiovascular and Renal Outcomes

Luís Corral-Gudino, Miriam Gabella-Martín, Álvaro Rodrigo-Alaíz, José Pablo Miramontes-González, David González-Calle, Juana Carretero-Gómez
article en

Abstract

Incretin-based therapy has shifted care from glucose-centric targets to cardiorenal risk reduction. GLP-1RA are guideline-endorsed for patients with T2DM and high CV/renal risk irrespective of HbA1c; dual agonists and oral small-molecule agents may broaden indications pending definitive outcome evidence.

Diabetes TherapyVol. 17(3)
Universidad de Valladolid (ES), Universidad de Salamanca (ES), Centro de Implantología Cirugía Oral y Maxilofacial (ES), Hospital Universitario Río Hortega (ES)
Good health and well-being
Openalex Percentile: Top 97%
Diabetes Treatment and Management
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