Impact of absolute lymphocyte count upon admission to ICU on 28-day mortality in sepsis patients in ICU

In sepsis patients, lymphopenia represents a significant high-risk factor, while the first absolute lymphocyte count (FALC) stands out as a clinically meaningful indicator. It allows for precise risk stratification of patients at the time of ICU admission, thereby enabling timely immune interventions that can effectively enhance prognostic outcomes.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-05
DOI
https://doi.org/10.3389/fimmu.2025.1688451
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Impact of absolute lymphocyte count upon admission to ICU on 28-day mortality in sepsis patients in ICU

Dingjun Zhong, Ling Zhao
Frontiers in Immunology
Sepsis Diagnosis and Treatment
article

Impact of absolute lymphocyte count upon admission to ICU on 28-day mortality in sepsis patients in ICU

Dingjun Zhong, Ling Zhao
article en

Abstract

In sepsis patients, lymphopenia represents a significant high-risk factor, while the first absolute lymphocyte count (FALC) stands out as a clinically meaningful indicator. It allows for precise risk stratification of patients at the time of ICU admission, thereby enabling timely immune interventions that can effectively enhance prognostic outcomes.

Frontiers in ImmunologyVol. 16
Xinjiang Medical University (CN), Zhuhai People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 98%
Sepsis Diagnosis and Treatment
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