The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions

KD demonstrates therapeutic potential in the management of a broad range of metabolic and neurological diseases; however, it is not an intervention suitable for all clinical situations. Awareness of existing contraindications, conditions requiring particular caution, and potential drug interactions enables a more responsible, individualised, and safe approach to patient selection and clinical management. In this context, the present paper provides a concise yet comprehensive synthesis to support clinicians and researchers in the rational and effective application of the ketogenic diet in both clinical practice and scientific research.

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Publication Details

Journal
Annals of Medicine
Published
2026-01-04
DOI
https://doi.org/10.1080/07853890.2025.2603016
Citations
2
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
65.68
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article

The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions

Dorota Łojko, Katarzyna Antosik, Damian Dyńka, David Unwin et al.
2 citations
Annals of Medicine
Diet and metabolism studies
65.68
article

The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions

Dorota Łojko, Katarzyna Antosik, Damian Dyńka, David Unwin, Żaneta Grzywacz, Georgia Ede, Łukasz Rodzeń, Mateusz Rodzeń, Hanna Karakuła-Juchnowicz, Shebani Sethi
article en
2 citations

Abstract

KD demonstrates therapeutic potential in the management of a broad range of metabolic and neurological diseases; however, it is not an intervention suitable for all clinical situations. Awareness of existing contraindications, conditions requiring particular caution, and potential drug interactions enables a more responsible, individualised, and safe approach to patient selection and clinical management. In this context, the present paper provides a concise yet comprehensive synthesis to support clinicians and researchers in the rational and effective application of the ketogenic diet in both clinical practice and scientific research.

Annals of MedicineVol. 58(1)
Opole University of Technology (PL), Poznan University of Medical Sciences (PL), Medical University of Lublin (PL), Edge Hill University (GB), University of Siedlce (PL), Hospital of the Brothers of St. John of God (AT), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 0%
Diet and metabolism studies
65.68
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The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions — Dorota Łojko, Katarzyna Antosik, et al. · Annals of Medicine (2026) | TGRS Research Map | TGRS