Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1–Nrf2 axis
The results of this study demonstrate that the nanodisks formulation developed in this work effectively enables stable encapsulation of GO, enhances its bioavailability, and improves its protective efficacy against LPS-induced ALI. Furthermore, this formulation provides a promising theoretical foundation for the encapsulation of oil-based pharmaceuticals.
Authors
- Ruilin Hou (ORCID: https://orcid.org/0009-0001-4915-3150)
- Xiaoying Yang (ORCID: https://orcid.org/0000-0001-8382-9719)
- Bowen Jiang (ORCID: https://orcid.org/0009-0005-9528-9832)
- Wenping Zhang
- Kai Wang
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fmolb.2025.1686436
- Primary Topic
- Garlic and Onion Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00