SARS-CoV-2 breakthrough infection among people with and without HIV in Ontario, Canada
We found that risk of SARS-CoV-2 breakthrough infection did not meaningfully differ between a population-based cohort of vaccinated people with HIV and a matched cohort of people without HIV after accounting for sociodemographic factors, previous SARS-CoV-2 infection, SARS-CoV-2 testing patterns and COVID-19 vaccine doses (14 December 2020 to 5 May 2024). However, rates of breakthrough infection were higher among men with HIV compared to without HIV during the pre-Omicron era.
Authors
- Catharine Chambers (ORCID: https://orcid.org/0000-0002-7959-7078)
- Sharon Walmsley (ORCID: https://orcid.org/0000-0002-3959-5692)
- Anita C. Benoit (ORCID: https://orcid.org/0000-0001-9863-0278)
- Muluba Habanyama
- John McCullagh
- Rahim Moineddin
- Gordon Arbess (ORCID: https://orcid.org/0000-0002-1303-4010)
- Devan Nambiar
- Nasheed Moqueet (ORCID: https://orcid.org/0000-0001-9123-482X)
- Sarah A. Buchan (ORCID: https://orcid.org/0000-0002-5286-8974)
- Vanessa Tran (ORCID: https://orcid.org/0000-0002-4584-2565)
- C L Cooper
- Ann N. Burchell
- Abigail E. Kroch
- Claire E. Kendall
- Lawrence Mbuagbaw
- Cassandra Freitas
- Jeffrey C. Kwong
- for the CHESS Study Team
Institutions
- University Health Network (CA)
- 3M (United States) (US)
- University of Ottawa (CA)
- Public Health Agency of Canada (CA)
- University of Toronto (CA)
- Scarborough Health Network (CA)
- Ottawa Hospital (CA)
- Women's College Hospital (CA)
- Central Hospital of Yaoundé (CM)
- Regent Park Community Health Centre (CA)
- Health Solutions (Sweden) (SE)
- Public Health Ontario (CA)
- Bruyère (CA)
- Institute for Clinical Evaluative Sciences (CA)
- Sexual Health Clinic (FI)
- Impact (CA)
- Digital Research Alliance of Canada
- Ottawa Hospital Research Institute (CA)
- HIV Legal Network (CA)
- St. Joseph’s Healthcare Hamilton (CA)
- McMaster University (CA)
Publication Details
- Journal
- AIDS
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1097/qad.0000000000004351
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00