Pharmacogenetic Predictors of Postoperative Opioid‐Related Adverse Events: A Systematic Review
While finding two significant associations, we would expect one to two significant associations at random given the 31 meta-analyses. Findings were limited by heterogeneity, few studies and small sample sizes. The current evidence does not suggest that genotypes should have a central place in the risk stratification of the occurrence of postoperative ORADEs.
Authors
- Kim Dalhoff (ORCID: https://orcid.org/0000-0002-5548-6381)
- Michael Asger Andersen (ORCID: https://orcid.org/0000-0001-9729-9974)
- Anders Peder Højer Karlsen (ORCID: https://orcid.org/0000-0002-0338-3751)
- Mathias Maagaard (ORCID: https://orcid.org/0000-0002-9037-7295)
- A Saito (ORCID: https://orcid.org/0000-0002-3023-3812)
- Pernille Bjersand Sunde (ORCID: https://orcid.org/0009-0008-8860-076X)
- Caroline Folkersen (ORCID: https://orcid.org/0009-0005-0783-3931)
- Selma Pedersen Kjartansdóttir (ORCID: https://orcid.org/0009-0007-5919-7118)
- Ida Rasmussen (ORCID: https://orcid.org/0009-0007-7290-5254)
Institutions
- University of Copenhagen (DK)
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Frederiksberg Hospital (DK)
- Copenhagen University Hospital (DK)
- Zealand University Hospital (DK)
- Zealand University Hospital Køge (DK)
- Pontifícia Universidade Católica de Campinas (BR)
- Pontifícia Universidade Católica de São Paulo (BR)
Publication Details
- Journal
- Basic & Clinical Pharmacology & Toxicology
- Published
- 2026-01-04
- DOI
- https://doi.org/10.1111/bcpt.70154
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00