Study on the mechanism of TMZ resistance in brain glioma regulated by copper death

TMZ resistance in glioma cells was affectively reversed by the cuproptosis pathway, a mechanism likely involving the activation of the intrinsic apoptotic pathway. This finding offered a novel strategy for overcoming TMZ resistance.

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Publication Details

Journal
Neurological Research
Published
2026-01-05
DOI
https://doi.org/10.1080/01616412.2025.2611013
Primary Topic
Trace Elements in Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Study on the mechanism of TMZ resistance in brain glioma regulated by copper death

Yongji Zhu, Jianglong Yu, Yabo Sun, Yufei Qu et al.
Neurological Research
Trace Elements in Health
article

Study on the mechanism of TMZ resistance in brain glioma regulated by copper death

Yongji Zhu, Jianglong Yu, Yabo Sun, Yufei Qu, Abudula Aisha, Yiderisi Aosiman
article en

Abstract

TMZ resistance in glioma cells was affectively reversed by the cuproptosis pathway, a mechanism likely involving the activation of the intrinsic apoptotic pathway. This finding offered a novel strategy for overcoming TMZ resistance.

Neurological Research
Xinjiang Medical University (CN), Second Affiliated Hospital of Xinjiang Medical University (CN)
Good health and well-being
Openalex Percentile: Top 97%
Trace Elements in Health
DOISourceOpenAlex
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Study on the mechanism of TMZ resistance in brain glioma regulated by copper death — Yongji Zhu, Jianglong Yu, et al. · Neurological Research (2026) | TGRS Research Map | TGRS