Gender-affirming hormone therapy and vascular health: walking the line between caution and confidence

This pilot study suggests a more pronounced progression of atherosclerosis in TW undergoing GAHT, detectable particularly through CCTA. These findings support refined CV monitoring and highlight the need for larger, long-term studies to guide preventive strategies in transgender populations.

Authors

Thierry Couffinhal (ORCID: https://orcid.org/0000-0002-9217-2533)
MARIE-ANGE RENAULT
Romane Lebourdon
Amandine Galioot
Sami Fawaz (ORCID: https://orcid.org/0000-0002-2817-4518)
Marion Camoin (ORCID: https://orcid.org/0000-0002-1388-2482)
Antoine Tabarin
Pierre Mora
V. Maury
Michel Montaudon
Virginie Grouthier

Institutions

Université de Bordeaux (FR)
Inserm (FR)
Centre Hospitalier Universitaire de Bordeaux (FR)
Hôpital Cardiologique du Haut-Lévêque (FR)

Publication Details

Journal: European Journal of Preventive Cardiology
Published: 2026-01-04
DOI: https://doi.org/10.1093/eurjpc/zwaf789
Primary Topic: LGBTQ Health, Identity, and Policy
Type: article
Field-Weighted Citation Impact: 0.00

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article

Gender-affirming hormone therapy and vascular health: walking the line between caution and confidence

Thierry Couffinhal, MARIE-ANGE RENAULT, Romane Lebourdon, Amandine Galioot et al.

Jan 4, 2026

European Journal of Preventive Cardiology

LGBTQ Health, Identity, and Policy

article

Gender-affirming hormone therapy and vascular health: walking the line between caution and confidence

Thierry Couffinhal, MARIE-ANGE RENAULT, Romane Lebourdon, Amandine Galioot, Sami Fawaz, Marion Camoin, Antoine Tabarin, Pierre Mora, V. Maury, Michel Montaudon, Virginie Grouthier

January 4, 2026article en

Abstract

This pilot study suggests a more pronounced progression of atherosclerosis in TW undergoing GAHT, detectable particularly through CCTA. These findings support refined CV monitoring and highlight the need for larger, long-term studies to guide preventive strategies in transgender populations.

European Journal of Preventive Cardiology

Université de Bordeaux (FR), Inserm (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Hôpital Cardiologique du Haut-Lévêque (FR)

Openalex Percentile: Top 98%

LGBTQ Health, Identity, and Policy

DOI Source OpenAlex

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