Schisandra chinensis alleviates Hypertriglyceridemia in nonalcoholic fatty liver disease by modulating the gut microbiota and hepatic lipid metabolism: identification of its active fractions

This integrative study demonstrates that SCH protects against NAFLD by lowering triglycerides, remodeling the gut-liver axis, and reprogramming hepatic lipid metabolism. The BuOH fraction constitutes the main active component, supporting SCH as a promising multi-target candidate for NAFLD therapy.