Case Report: A case of cervical burkitt lymphoma and literature review
Primary cervical Burkitt's lymphoma (BL) is an extremely rare malignancy. This report describes the case of a 55-year-old woman admitted to the hospital with irregular vaginal bleeding. Histologically, the tumor cells demonstrated infiltrative growth, relatively uniform basophilic cytoplasm. Immunohistochemical analysis revealed positivity for B-cell markers (CD20, CD79α, etc.), with MYC expression in approximately 80% of cells, fluorescence <i>in situ</i> hybridization staining showed positivity for MYC translocation and molecular testing confirmed IG rearrangement. The diagnosis of Burkitt's lymphoma is based on its distinctive histological morphology in combination with immunohistochemistry and molecular testing.
Authors
- Sen Miao
- Hua Hao
- Yue Bai
Institutions
- Affiliated Hospital of Jining Medical University (CN)
- Yangpu Hospital of Tongji University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fonc.2025.1696219
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- Tongji University