Association of 41 circulating inflammatory factors, C-reactive protein, and procalcitonin with sepsis risk and 28-day mortality: A bidirectional Mendelian randomization and mediation analysis
This study enhances our understanding of the mechanisms underlying sepsis and its associated mortality, and underscores the therapeutic potential of targeting inflammatory factors in its management.
Authors
- Sheng Xie (ORCID: https://orcid.org/0000-0003-4276-3068)
- Bingbing Lei
- Jinchan Peng
- Jinjing Tan
- Guangyao Wang
- Jinxiu Wei
- Lijian Liu
- Liqun Li
Institutions
- Guangxi University (CN)
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
- Guangxi University of Chinese Medicine (CN)
Publication Details
- Journal
- Advances in Clinical and Experimental Medicine
- Published
- 2026-01-05
- DOI
- https://doi.org/10.17219/acem/203155
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 31.52
Funders
- National Natural Science Foundation of China
- Science and Technology Department of Guangxi Zhuang Autonomous