The utility of genomics and functional imaging to predict sunitinib pharmacokinetics and pharmacodynamics: The predict SU study

Exploratory associations were observed between sunitinib PK/PD with hepatic functional imaging with extensive pharmacogenomics. Further validation is required.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2026-01-04
DOI
https://doi.org/10.1002/bcp.70431
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

The utility of genomics and functional imaging to predict sunitinib pharmacokinetics and pharmacodynamics: The predict SU study

M. Burge, A Matera, Ian Campbell, E. Link et al.
British Journal of Clinical Pharmacology
Lung Cancer Treatments and Mutations
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The utility of genomics and functional imaging to predict sunitinib pharmacokinetics and pharmacodynamics: The predict SU study

M. Burge, A Matera, Ian Campbell, E. Link, Guy C. Toner, Rodney J. Hicks, Simone M. Rowley, Christos S. Karapetis, David Pook, Mick Thompson, Michael Michael, Vinod Ganju
article en

Abstract

Exploratory associations were observed between sunitinib PK/PD with hepatic functional imaging with extensive pharmacogenomics. Further validation is required.

British Journal of Clinical Pharmacology
The University of Melbourne (AU), Royal Brisbane and Women's Hospital (AU), Peter MacCallum Cancer Centre (AU), Monash Medical Centre (AU), Flinders Medical Centre (AU), Peninsula Health (AU)
Openalex Percentile: Top 98%
Lung Cancer Treatments and Mutations
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