Cluster-randomized evaluation of neonatal intensive care unit quality improvement interventions in extremely preterm infants: secondary analysis of the INTACT trial
This secondary analysis of a cluster-randomized controlled trial demonstrated that the intervention group receiving a NICU-specific QI program had reduced acute-phase morbidities, particularly among infants born between 22 and 27 weeks of gestation. Our findings highlight the potential for widespread clinical implementation of QI programs based on participatory learning and action in neonatal intensive care.
Authors
- Hirosato Aoki (ORCID: https://orcid.org/0000-0002-8558-7693)
- Yumi Kono
- Tomoyuki Shimokaze (ORCID: https://orcid.org/0000-0001-8490-475X)
- Naohiro Yonemoto (ORCID: https://orcid.org/0000-0003-3637-2095)
- Hideko Mitsuhashi
- Rintaro Mori
- INTACT Study Group
- Satoshi Kusuda
- Hatoko Sasaki
- Toshihiko Nishida
- Masanori Fujimura
- Tomoko Saito
- Atsushi Uchiyama
- Katsuaki Toyoshima
Institutions
- Shizuoka University (JP)
- Tokai University (JP)
- Jichi Medical University (JP)
- University of Shizuoka (JP)
- Juntendo University (JP)
- Osaka Women's and Children's Hospital (JP)
- Kanagawa Children's Medical Center (JP)
- National Center For Child Health and Development (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1186/s12887-025-06351-8
- Primary Topic
- Infant Development and Preterm Care
- Type
- article
- Field-Weighted Citation Impact
- 0.00